Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Hypertrophic cardiomyopathy Characterised by myocardial hypertrophy,abnormal diastolic filling,intermittent ventricular outflow obstruction Related to defects in force generation owing to altered sarcomeric function Leading cause of LVH,unexplained by other clinical/pathologic cause Caused by mutation of genes encoding sarcomeric proteins Boasting an impressive range of designs, they will support your presentations with inspiring background photos or videos that support your themes, set the right mood, enhance your credibility and inspire your audiences. ... - Cardiomyopathy in neonates and children Dr Rajesh Kumar MD (PGI), DM (Neonatology) PGI, Chandigarh, India Rani Children Hospital, Ranchi Some cardiomyopathies are ... Clinical sensitivity of molecular genetic testing in hypertrophic cardiomyopathy. 14. And, best of all, most of its cool features are free and easy to use. Hypertrophic Non-Obstructive Cardiomyopathy (HNCM) is a subtype of hypertrophic cardiomyopathy, which is a condition affecting the heart muscle The term “hypertrophic” means enlargement of cells, which, in this condition, leads to a thickening of the heart muscle. Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiovascular disorder, representing a leading cause of sudden cardiac death in the young and a prevalent cause of heart failure and stroke. If so, share your PPT presentation slides online with PowerShow.com. Hypertrophic cardiomyopathy (HCM) is a genetically determined heart muscle disease most often (60 to 70 percent) caused by mutations in one of several sarcomere genes which encode components of the contractile apparatus of the heart. Atrial fibrillation (AF) is frequently associated with HCM with a reported prevalence of about 20% to 25%. When this happens, the ventricle has to work harder to pump out blood. - Cardiomyopathy (literally "heart muscle disease") is the measurable deterioration of the function of the myocardium (the heart muscle) for any reason usually leading to heart failure. Takotsubotype cardiomyopathy due to multivesselspasm. The disease has complex symptomatology and potentially devastating consequences for … The mitral valve can also be affected and is unable to close properly. Early Detection of Hypertrophic Cardiomyopathy, - Title: Slide 1 Author: mwiegand Last modified by: June Hanks Created Date: 4/15/2008 10:37:56 PM Document presentation format: On-screen Show (4:3) Company. These proteins, namely beta-myosin heavy chain, myosin-binding protein C and cardiac troponin C, are structurally important in cardiac muscle. - Title: PowerPoint Presentation Author: Scott Johnson Last modified by: Authorised User Created Date: 3/10/2009 8:02:56 PM Document presentation format, Cardiomyopathy : Causes, Symptoms,Types, Diagnosis and Treatment (1). Alcohol septal ablation. Summary. Genetic Etiology of Hypertrophic Cardiomyopathy (HCM) ~30-60% of HCM patients have an identifiable pathogenic or likely-pathogenic genetic variant Many others have no genetic evidence of disease and / or ... Cardiomyopathy Pathophysiology. Change in stress leads to adaptations. Primary cardiomyopathies 3.1.1 Genetic 3.1.1.1 Hypertrophic cardiomyopathy HCM is a condition of the heart in … Cardiac hypertrophy is usually asymmetrical with greatest involvement most commonly of the basal interventricular septum subjacent to the aortic valve. Clipping is a handy way to collect important slides you want to go back to later. No public clipboards found for this slide. 22: Figure 1. HCM is an inherited (autosomal dominant) disease of the myocardium. Hypertrophic cardiomyopathy (HCM) has been defined morphologically by unexplained hypertrophy in the absence of haemodynamic stress, and at the histological level by myocyte disarray, fibrosis, and abnormalities of the intramyocardial small vessels. Five patients, all women, age ranges 59 to 84 years, with underlying hypertrophic obstructive cardiomyopathy (HOCM) presented with profound hypotension. Through a distal port on the balloon-tipped catheter,1-3 mL of ethanol is injected into the septal artery resulting in a controlled myocardial infarction. INTRODUCTION. ... Cardiomyopathy Pathophysiology. Classification and Definitions of Cardiomyopathies 9 3.1. It is occasionally restricted to other myocardial regions, such as the apex, the midportion, and the posterior wall of the left ventricle… What Causes Hypertrophic Cardiomyopathy? Up to 60% of the cases are due to mutations in TM, 54, WAS ADMITTED to the ED after a syncopal episode that resulted in a head injury. Aetiology. 16. 2,3 Recognised autosomal dominant mutations within sarcomere proteins are found in 55 % of adolescents with sporadic HCM. D. Aortic stenosis. In: Kodama K, Haze, K, Hon M, editors. CARDIOMYOPATHY BY: RICHARD KAMINSKI DESCRIPTION OF DISEASE • Hypertrophic cardiomyopathy (HCM) occurs if heart muscle cells enlarge and cause the walls of the ventricles (usually the left ventricle) to thicken. In the early stages of cardiomyopathy, there may be no symptoms at all. We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. Hypertrophic cardiomyopathy (HCM) (see the image below) is a genetic disorder that is typically inherited in an autosomal dominant fashion with variable penetrance and variable expressivity. Cardiomyopathy Medication Market-Global Forecast to 2025. Hypertrophic cardiomyopathy (HCM) is a primary and usually familial cardiac disorder with heterogeneous expression, unique pathophysiology, and a diverse clinical course, for which several disease-causing mutations in genes encoding proteins of the sarcomere have been reported.1–7 Because of the characteristic clinical, morphological, and genetic diversity, HCM has held the curiosity … See our User Agreement and Privacy Policy. Over the years, classification of this condition has been updated by the rapid advancement of genetic, imaging, and clinical investigation. It's FREE! In other instances, the cause is unknown. Same group from Mayo Clinic Compared treatment effects of dual-chamber pacing versus septal myectomy Non-randomized prospective trial of 39 patients: 20  myectomy / 19  pacing Myectomy: greater reduction in LVOT gradients, larger improvements in NYHA class, exercise time, oxygen consumption. Hypertrophic cardiomyopathy (HCM) is a condition in which the heart becomes thickened without an obvious cause. Introduction. Hypertrophic cardiomyopathy (HCM) is the most common monogenic cardiovascular disorder, affecting one of every 500 adults.It is found across all racial groups and is the most common cause of sudden death in young athletes ().The disease is characterized by left ventricular (LV) hypertrophy in the absence of another systemic or cardiac disease to account for the changes noted. In 2010, the Study Group on peripartum cardiomyopathy of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC) defined PPCM as an idiopathic cardiomyopathy occurring towards the end of pregnancy or in the months following delivery, abortion or miscarriage, without other causes for heart failure, and with a left ventricular (LV) ejection fraction (EF) < 45% 5 (see Box). In 2010, the Study Group on peripartum cardiomyopathy of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC) defined PPCM as an idiopathic cardiomyopathy occurring towards the end of pregnancy or in the months following delivery, abortion or miscarriage, without other causes for heart failure, and with a left ventricular (LV) ejection fraction (EF) < 45% 5 (see Box). Genetic Etiology of Hypertrophic Cardiomyopathy (HCM) ~30-60% of HCM patients have an identifiable pathogenic or likely-pathogenic genetic variant Many others have no genetic evidence of disease and / or Hypertrophic cardiomyopathy (HCM) (see the image below) is a genetic disorder that is typically inherited in an autosomal dominant fashion with variable penetrance and variable expressivity. Cardiomyopathy is any structural and functional abnormality of the heart muscle unattributable to specific causes or disease processes such as coronary artery disease (CAD), congenital heart disease, or valvular disease. Looks like you’ve clipped this slide to already. Evaluation and Testing for HCM. Atrial fibrillation (AF) is frequently associated with HCM with a reported prevalence of about 20% to 25%. Powerpoint slides. Aetiology. Sato H, TateishiH, Uchida T, et al. Initial clinical and hemodynamic evaluation suggested cardiogenic shock in two cases, acute myocardial ischemia in two cases, and hypovolemia in one case. Cardiomyopathy: Pathophysiology and Assessment RobertoMLang,MD Circ J 2004; 68: 77-81 Japanese word for octopus catcher Tako-Tsubo Cardiomyopathy Broken Heart Syndrome Apical Balooning 1. HCM, which occurs in 0.2% of the general population, is the most common cause of sudden cardiac death in young people. Our new CrystalGraphics Chart and Diagram Slides for PowerPoint is a collection of over 1000 impressively designed data-driven chart and editable diagram s guaranteed to impress any audience. Hypertrophic cardiomyopathy (HCM) is a genetic disorder of cardiac myocytes that is characterized by cardiac hypertrophy, unexplained by the loading conditions; a nondilated left ventricle; and a normal or increased ejection fraction. 1996;94:850-56. A J Marian (Jan 1, p 58)1 postulates that cardiac contractility is decreased in hypertrophic cardiomyopathy (HCM) and that the preserved or increased ejection fraction observed in patients with HCM is a result of the concentric nature of the hypertrophy. - Famous for being leading cause of sudden cardiac death in young athletes ... Enlarged septum narrows left ventricle outflow tract. The septal artery catheter balloon is inflated preventing backwash of alcohol into the remainder of the coronary tree. Cardiomyopathies are diseases of the muscle tissue of the heart.Types of cardiomyopathies include dilated, hypertrophic, restrictive, and arrhythmogenic right ventricular cardiomyopathy. The main pathophysiology behind is that every organ is in homeostasis with physiological stress. Over the years, classification of this condition has been updated by the rapid advancement of genetic, imaging, and clinical investigation. Hypertrophic cardiomyopathy (HCM) is the most common monogenic cardiovascular disorder, affecting one of every 500 adults.It is found across all racial groups and is the most common cause of sudden death in young athletes ().The disease is characterized by left ventricular (LV) hypertrophy in the absence of another systemic or cardiac disease to account for the changes noted. And they’re ready for you to use in your PowerPoint presentations the moment you need them. The parts of the heart most commonly affected are the interventricular septum and the ventricles. ... An 80-year-old African-American woman is admitted to the hospital under your ... - Hypertrophic Cardiomyopathy Board Review Rami Khouzam, MD ... Congestive dilated cardiomyopathy. Caused by blockages in coronary arteries ... Mimics myocardial infarction ... Alpha and beta blockers the best treatment. 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